Quantitative Susceptibility Mapping at 7T Using Bilateral Orthogonality Generative Acquisitions Method

Motivation: Effect of transmit field inhomogeneity on SNR at 7T, plays a critical role in high resolution Quantitative Susceptibility Mapping (QSM). Goal(s): Implementation of Bilateral Orthogonality Generative Acquisitions (BOGA) for mitigation of the effects of low signal intensity and signal dropouts on QSM. Approach: Using 8-channel parallel transmission system, two multi-echo GRE acquisitions with different RF modes are utilized for BOGA method and compared against conventional data acquisition for QSM. Results: BOGA method eliminates the distortion due to transmit field inhomogeneity in susceptibility maps due to the increased SNR in low intensity regions, such as cerebellum. Impact: Effects of the transmit field inhomogeneity on susceptibility mapping can be eliminated with BOGA method, particularly at lower brain regions. Which can further increase the utilization of susceptibility mapping in lower brain regions.