Magnetic Particle Imaging angiography in a human cadaveric perfusion model
Motivation: Magnetic Particle Imaging (MPI) is a radiation-free imaging technique particularly appealing for clinical applications, where reducing radiation exposure is crucial. Goal(s): Investigating the feasibility of MPI for real-time vascular imaging and its potential as a clinically viable imaging tool. Approach: To simulate real-life conditions, a portable MPI scanner for human application in combination with an X-ray system was tested on human cadaveric specimens with continuous perfusion. Results: The results demonstrated reliable visualization of femoral arteries with high temporal resolution, underscoring MPI's potential as a safe, effective complement to traditional vascular imaging. This approach is particularly beneficial for interventional radiology. Impact: MPI offers a radiation-free alternative for real-time vascular imaging, improving patient safety, especially in sensitive populations. With its high-resolution, dynamic imaging capabilities the integration into clinical settings could reduce/remove ionizing radiation and associated risks in interventional radiology.
Authors
- Florian Kleefeldt (ORCID: https://orcid.org/0009-0007-7751-0403)
- Stefan Herz (ORCID: https://orcid.org/0000-0002-6360-0578)
- Thomas Kampf (ORCID: https://orcid.org/0000-0002-9905-0184)
- Jillian R. Gunther (ORCID: https://orcid.org/0000-0001-5727-7594)
- Dominik Peter (ORCID: https://orcid.org/0009-0006-3060-6304)
- Philipp Gruschwitz (ORCID: https://orcid.org/0000-0002-2565-8111)
- Süleyman Ergün (ORCID: https://orcid.org/0000-0002-2112-5377)
- Patrick Vogel (ORCID: https://orcid.org/0000-0003-0801-5146)
- Martin Rückert (ORCID: https://orcid.org/0000-0002-5608-5627)
- Volker C. Behr (ORCID: https://orcid.org/0000-0002-2362-3388)
- Jan‐Peter Grunz (ORCID: https://orcid.org/0000-0002-4524-1620)
- Teresa Reichl (ORCID: https://orcid.org/0000-0002-6992-117X)
- Thorsten Alexander Bley (ORCID: https://orcid.org/0000-0001-9311-7985)
- Anne Marie Augustin (ORCID: https://orcid.org/0000-0002-3541-5287)
- Viktor Hartung (ORCID: https://orcid.org/0000-0002-6273-9172)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/4988
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00