Accelerated large FOV TSE body imaging at 7T using local contrast optimized AMORE

Motivation: Large field of view TSE imaging at UHF remains elusive. Goal(s): 1) Elucidate requirements needed for repetition time reduction while maintaining contrast to noise ratio (CNR). 2) Create a loss function that explicitly enforces this condition. Approach: Perform prostate and kidney TSE experiments at 7T with different repetition times and two TIAMO modes optimized for contrast and SAR calculated from a new loss function, demonstrating performance tradeoffs. Results: Reduced TR imaging using localized AMORE modes maintained prostate contrast and filled signal voids. The new contrast optimization enabled kidney acquisitions; demonstrating high scan efficiency and image quality in large FOV TSE imaging at 7T. Impact: A generalization of the AMORE method, AMORE-C, is developed that enables TSE imaging using a TR half that of standard TSE sequences. This method has minimal SAR penalties and enables large FOV imaging in the body with improved scanning efficiency.