Value of dynamic contrast-enhanced MRI in the diagnosis of acute radiation-induced rectal injury: a comparison with endoscopy
Motivation: The postoperative anastomotic fistula of rectal cancer is affected by radiation proctitis. Radiation proctitis is mainly evaluated by endoscopy, which is invasive and subjective. Goal(s): To investigate the value of DCE-MRI parameters in diagnosising acute radiation-induced rectal injury. Approach: In a retrospective analysis, DCE-MRI parameters of rectal wall in 49 patients after neoadjuvant chemoradiotherapy were measured and compared with the evaluation of Vienna endoscopy. Results: Ktrans in patients with acute RRI was significantly lower compared to those without acute RRI, with a AUC of 0.80. Impact: DCE-MRI is an appropriate non-invasive imaging technique for diagnosing acute RRI in patients with rectal cancer.
Authors
- Yan Ma (ORCID: https://orcid.org/0000-0002-3559-4393)
- Jing Yuan (ORCID: https://orcid.org/0000-0001-8112-3608)
- Yaou Liu (ORCID: https://orcid.org/0000-0002-2965-0766)
- Yan Chen (ORCID: https://orcid.org/0000-0003-1287-4525)
- Song Yu
- Baolan Lu (ORCID: https://orcid.org/0000-0002-8393-5017)
- Zhibo Wen (ORCID: https://orcid.org/0000-0002-0497-0923)
- Wenjie Fan (ORCID: https://orcid.org/0000-0003-4332-3697)
- Qingyu Liu (ORCID: https://orcid.org/0000-0001-7171-6346)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/5165
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00