Prostate MR Fingerprinting T1 and T2 quantification at 0.55T using tensor denoising

Motivation: Identifying prostate lesions at 0.55T using T1 and T2 values from MR Fingerprinting could expand access to quantitative techniques, though low SNR raises precision & accuracy concerns. Goal(s): To evaluate the accuracy, precision and robustness of prostate T1 and T2 values from MRF at 0.55T. Approach: Tensor denoising was applied to MRF acquisitions. Maps accuracy and precision after tensor denoising were evaluated in phantom. Different coils setups were evaluated in vivo. Results: Phantom & in vivo experiments confirm tensor denoising robustness across different noise levels. T1 and T2 values of prostate lesions from 7 subjects were reported at 0.55T. Impact: We show prostate lesions' T1 and T2 values from 0.55T MR Fingerprinting can be detected with statistical significance. By assessing accuracy, precision and robustness to noise, we potentially enable the study of prostate cancer quantitative characterization at 0.55T.