Cardiac contractility and ventricular efficiency are predictive of adverse cardiac remodeling independent of infarct size in STEMI patients

Motivation: Current methods in clinical practice is unable to accurately predict adverse cardiac remodeling after ST-elevation myocardial infarction (STEMI). Goal(s): To predict adverse cardiac remodeling in patients acutely after STEMI. Approach: Applying non-invasive pressure-volume loop (PV-loop) variables by cardiovascular magnetic resonance (CMR) in STEMI-patients from The Third DANish Study of Optimal Acute Treatment of Patients with STEMI (DANAMI-3). Results: Contractility and ventricular efficiency were predictive of adverse cardiac remodeling independent of age, sex, and infarct size. Impact: Non-invasive PV-loops could be used early after STEMI in risk assessment for adverse cardiac remodeling.