Directional M1-Optimized DWI for Robust Motion-compensation and Blood-suppressed Liver Imaging

Motivation: Liver diffusion-weighted imaging (DWI) often suffers from motion artifacts from cardiac motion. Previous motion compensation techniques result in residual bright blood signals that complicate image interpretation. Goal(s): To develop a directional M1-optimized DWI sequence that adjusts the diffusion gradient's M1 value across different axes to enhance motion compensation and blood signal suppression. Approach: We designed a directional M1-optimized DWI technique based on conventional DWI sequence, adjusting the diffusion gradients for specific physical axes. Results: The results showed reduced blood signal, more uniform signal intensities and ADC values in the liver, indicating effective blood suppression and motion compensation. Impact: This technique enhances motion compensation and blood signal suppression in liver DWI, providing clearer and more accurate liver assessments. This technique may improve diagnostic capabilities in various imaging applications, potentially benefiting broader areas such as breast and brain imaging.