Resting-state functional connectivity in mouse cervical spinal cord at 15.2T

Motivation: Resting-state functional connectivity in mice spinal cord has not been reported previously Goal(s): To identify resting-state functional circuits within the spinal cord of mice Approach: We used 15.2T MRI to detect the intrinsic BOLD signals in mouse spinal cords and calculated inter-voxel correlations in a resting state to delineate networks Results: We found resting-state functional circuits were robustly detectable within gray matter in the mouse spinal cord similar to those reported for other species. Impact: This work shows the potential to detect BOLD signals in mouse spinal cords and derive network characteristics in mouse models of different disorders.