Wireless Integrated Sensing Detector for simultaneous EEG and MRI (WISDEM)

Motivation: Perform simultaneous EEG and fMRI using a compact and wireless detector that can continuously record EEG signals in the presence of switching gradients. Goal(s): However, MRI scanners generate tremendous artifacts for EEG detection. Approach: A Wireless Integrated Sensing Detector for simultaneous EEG and MRI (WISDEM) is developed to encode fMRI and EEG signals on distinct sidebands of the detector's oscillation carrier wave for detection by a standard MRI console over the entire duration of fMRI sequence. Results: From optogenetically-stimulated somatosensory cortex, the positive correlation between evoked LFP and fMRI signals validates strong neurovascular coupling. Impact: This 2-in-1 transducer will enable cross-scale brain mapping.