Perfusion imaging with arterial spin labeling (ASL)-MRI for non-invasive treatment monitoring of patients with acute pulmonary embolism
Motivation: Antithrombotic treatment of patients with pulmonary embolism (PE) is not monitored routinely and treatment effectiveness is often unknown. Goal(s): Our goal was to assess the feasibility of arterial spin labeling (ASL) MRI to monitor treatment effects in patients with PE. Approach: 15 patients of initially 107 patients with PE underwent follow-up imaging with ASL-MRI. Results: A significant improvement in perfusion was observed in all patients after treatment. 8 of 15 patients showed remaining pulmonary perfusion defects. There was a significant correlation between remaining dyspnea and the detection of perfusion defects after treatment. Impact: Arterial spin labeling (ASL)- MRI demonstrates the potential to monitor pulmonary perfusion changes in patients with pulmonary embolism under therapy.
Authors
- Petros Martirosian (ORCID: https://orcid.org/0000-0001-8383-0883)
- Konstantin Nikolaou (ORCID: https://orcid.org/0000-0003-2668-7325)
- Yasmin Komma (ORCID: https://orcid.org/0000-0002-4431-1973)
- Brigitte Gückel (ORCID: https://orcid.org/0000-0001-7761-7592)
- Cecilia Liang (ORCID: https://orcid.org/0000-0002-6937-1681)
- Ferdinand Seith (ORCID: https://orcid.org/0000-0002-9696-2954)
- Dominik Rath (ORCID: https://orcid.org/0000-0002-5008-2572)
- R Pohmann (ORCID: https://orcid.org/0000-0002-6137-9590)
- Max Munz (ORCID: https://orcid.org/0000-0001-6931-1489)
- Meinrad Gawaz (ORCID: https://orcid.org/0000-0003-1124-9592)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/3031
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00