Multi-Scanner harmonized 8-year longitudinal hip cartilage T1ρ and T2
Motivation: Longitudinal T1ρ and T2 measurements can help to understanding hip cartilage degeneration. However, inter-scanner variability introduces biases, complicating data interpretation. Goal(s): Harmonize scanner-related batch effects in longitudinal hip cartilage T1ρ and T2 data over an eight-year follow-up. Approach: The longitudinal ComBat method was used to mitigate scanner-induced biases and ensure data consistency. Results: ComBat harmonization effectively reduced scanner biases. Analysis showed an increase in T1ρ and T2, particularly in females aged 50 and above. Impact: The harmonized longitudinal T1ρ and T2 data provides insights into hip cartilage degeneration, aiding in understanding osteoarthritis progression.
Authors
- Yanjun Qian (ORCID: https://orcid.org/0000-0002-1581-0431)
- Valentina Pedoia (ORCID: https://orcid.org/0000-0002-9745-955X)
- Richard B. Souza (ORCID: https://orcid.org/0000-0001-7556-4132)
- Zheren Zhu (ORCID: https://orcid.org/0000-0002-8378-5063)
- Sharmila Majumdar (ORCID: https://orcid.org/0000-0002-0201-871X)
- Rafeek Thahakoya (ORCID: https://orcid.org/0000-0001-5593-7640)
- Rupsa Bhattacharjee (ORCID: https://orcid.org/0000-0001-9893-3527)
- Misung Han (ORCID: https://orcid.org/0000-0003-0918-8831)
- Yang Yang (ORCID: https://orcid.org/0000-0002-1367-1570)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/0557
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00