Modular integration of spatial-spectral selective excitation into Bruker Singlepulse, Flash, and EPI for metabolite selective HP 13C MRSI
Motivation: Metabolite-selective MR imaging via spatial-spectral excitation has become an important method in hyperpolarized 13C MRI. Open-access optimization tools provide numerous RF & gradient solutions for a desired spatial-spectral band. Goal(s): To provide solutions for users to test and verify the RF & gradient shape options via using standard MRI methods. Approach: In this work, we implemented a modular feature in Bruker ParaVision that allows the selection of customized pulses & gradients in product methods. Results: The feature was successfully implemented and tested in Singlepulse, FLASH, and EPI methods with minimal necessary reprogramming. Exemplary simulated and measured excitation profiles are presented. Impact: A modular framework for spatial-spectral excitation with Bruker product methods was implemented. The framework can assist MRI researchers to evaluate possible RF & gradient shapes for a specified metabolite-selective MR exam.
Authors
- Christoph Müller (ORCID: https://orcid.org/0000-0002-8187-9170)
- James W. Gaubatz
- Alastair Marshall (ORCID: https://orcid.org/0000-0001-7772-2173)
- Luca Nagel (ORCID: https://orcid.org/0000-0002-5530-6264)
- Franz Schilling (ORCID: https://orcid.org/0000-0001-5239-4628)
- Volker Rasche (ORCID: https://orcid.org/0000-0001-8844-3583)
- Ilai Schwartz (ORCID: https://orcid.org/0009-0001-5621-859X)
- S.J. Hedge
- Julian Schüle
- Pascal Rütten
- Shai Machnes
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/4482
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00