Modular integration of spatial-spectral selective excitation into Bruker Singlepulse, Flash, and EPI for metabolite selective HP 13C MRSI

Motivation: Metabolite-selective MR imaging via spatial-spectral excitation has become an important method in hyperpolarized 13C MRI. Open-access optimization tools provide numerous RF & gradient solutions for a desired spatial-spectral band. Goal(s): To provide solutions for users to test and verify the RF & gradient shape options via using standard MRI methods. Approach: In this work, we implemented a modular feature in Bruker ParaVision that allows the selection of customized pulses & gradients in product methods. Results: The feature was successfully implemented and tested in Singlepulse, FLASH, and EPI methods with minimal necessary reprogramming. Exemplary simulated and measured excitation profiles are presented. Impact: A modular framework for spatial-spectral excitation with Bruker product methods was implemented. The framework can assist MRI researchers to evaluate possible RF & gradient shapes for a specified metabolite-selective MR exam.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2025-09-16
DOI
https://doi.org/10.58530/2025/4482
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Modular integration of spatial-spectral selective excitation into Bruker Singlepulse, Flash, and EPI for metabolite selective HP 13C MRSI

Christoph Müller, James W. Gaubatz, Alastair Marshall, Luca Nagel et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Advanced MRI Techniques and Applications
article

Modular integration of spatial-spectral selective excitation into Bruker Singlepulse, Flash, and EPI for metabolite selective HP 13C MRSI

Christoph Müller, James W. Gaubatz, Alastair Marshall, Luca Nagel, Franz Schilling, Volker Rasche, Ilai Schwartz, S.J. Hedge, Julian Schüle, Pascal Rütten, Shai Machnes
article en

Abstract

Motivation: Metabolite-selective MR imaging via spatial-spectral excitation has become an important method in hyperpolarized 13C MRI. Open-access optimization tools provide numerous RF & gradient solutions for a desired spatial-spectral band. Goal(s): To provide solutions for users to test and verify the RF & gradient shape options via using standard MRI methods. Approach: In this work, we implemented a modular feature in Bruker ParaVision that allows the selection of customized pulses & gradients in product methods. Results: The feature was successfully implemented and tested in Singlepulse, FLASH, and EPI methods with minimal necessary reprogramming. Exemplary simulated and measured excitation profiles are presented. Impact: A modular framework for spatial-spectral excitation with Bruker product methods was implemented. The framework can assist MRI researchers to evaluate possible RF & gradient shapes for a specified metabolite-selective MR exam.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 63%
Advanced MRI Techniques and Applications
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