Towards reproducible perivascular space quantification: an open-source perivascular space segmentation benchmark

Motivation: The lack of open-source perivascular space (PVS) segmentation code hampers reproducible research, leading to redundant efforts, and hindering broader implementation of PVS segmentation. Goal(s): To create an open-source PVS segmentation benchmark. Approach: Phase 1: We engaged the PVS research community to contribute code to our open-source repository. We are currently collecting, verifying, and containerizing code submissions. Phase 2: We plan to compare submitted code against each other and a manually segmented ground truth benchmark. Our goal is to develop community guidelines based on input data. Results: We have received several code contributions and have issued an open call for more submissions. Impact: The efforts of the PVS repository team will establish an open-source platform for software code related to PVS quantification, minimizing duplicate development, enhancing reproducibility, and providing a benchmark for future development and comparison of segmentation methods.