Individually optimized dynamic parallel transmit pulses for 3D high-resolution SPACE imaging at 7T
Motivation: 3D high-resolution SPACE imaging at 7T suffers from signal dropouts due to inhomogeneous B1+ fields. Goal(s): To investigate online-optimized pTx pulses for homogenous SPACE brain imaging. Approach: Non-parametrized pTx pulses were designed for inversion, and, with symmetric RF and gradient shapes, for excitation and refocusing. The pulses are then individually optimized online within a clinically acceptable computation time. T1-weighted, T2-weighted, FLAIR and DIR SPACE images were acquired in five healthy subjects at 7T using both circularly polarized (CP) and dynamic pTx pulses for comparison. Results: Improved flip angle homogeneity was observed in all images acquired with individual pTx pulses as opposed to CP. Impact: Individually optimized dynamic parallel transmit pulses for 3D high-resolution SPACE imaging at 7T achieve clinically acceptable image homogeneity and acquisition time, enabling the application of widely used clinical contrasts at 7T.
Authors
- Tom Hilbert (ORCID: https://orcid.org/0000-0001-8207-4908)
- Patrick Alexander Liebig (ORCID: https://orcid.org/0000-0001-7342-3715)
- Dominik M. Nickel (ORCID: https://orcid.org/0000-0002-0360-7233)
- Robin Martin Heidemann (ORCID: https://orcid.org/0000-0001-7556-7405)
- Bénédicte Maréchal (ORCID: https://orcid.org/0000-0001-7866-2854)
- Gian Franco Piredda (ORCID: https://orcid.org/0000-0002-8449-6634)
- Jocelyn Philippe (ORCID: https://orcid.org/0009-0009-5952-6107)
- Tommaso Di Noto (ORCID: https://orcid.org/0000-0002-5161-055X)
- Thomas Yu (ORCID: https://orcid.org/0000-0002-5841-0198)
- Antoine Klauser (ORCID: https://orcid.org/0000-0003-3019-9914)
- Tobias Kober (ORCID: https://orcid.org/0000-0001-7598-9456)
- Emilie Sleight (ORCID: https://orcid.org/0000-0003-0034-4578)
- Lina Bacha
- Juergen Herrler
- Natalia Pato Montemayor (ORCID: https://orcid.org/0009-0006-7212-1970)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/3447
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00