Potential association between cognitive impairment and pre-pregnancy Body mass index in women with preeclampsia

Motivation: There is no study on magnetic resonance structural imaging combined with cognitive related proteins to evaluate brain damage in preeclampsia patients Goal(s): The objective of this study was to explore the specific neuroimaging manifestations of PE patients and their potential correlation with cognitive impairment. Approach: Voxel-based morphometry (VBM) was used to analyze the differences in gray matter volume (GMV) among the three groups. Results: The specific brain structural changes in PE patients were reduced GMV in the right middle temporal gyrus and superior temporal gyrus. Impact: Our findings suggest that the reduction of GMV volume in bilateral frontal and temporal lobes in PE patients can be used as a potential neuroimaging indicator of brain injury.