Association of post-treatment hyperperfusion with fluid-attenuated inversion recovery vascular hyperintensity in stroke patients

Motivation: Identifying a simpler marker to assess post-treatment perfusion in patients with acute ischemic stroke. Goal(s): The aim was to determine whether fluid-attenuated inversion recovery vascular hyperintensity (FVH) could be a potential surrogate marker for post-treatment perfusion in AIS patients. Approach: This retrospective clinical study classified M1-M6 regions of AIS patients into four groups based on the negative or positive of DWI and FVH. Perfusion of regions in each group was assessed and statistically analyzed. Results: A correlation was found between FVH and post-treatment perfusion. Hyperperfusion in the infarcted region was significantly correlated with FVH. Impact: Our study helps to determine whether FVH can serve as an imaging marker of post-treatment perfusion in AIS patients, enabling rapid assessment of perfusion in the absence of hemodynamic imaging, influencing therapeutic decisions, and optimizing patient outcomes.