Silent 3D MRSI at Ultrasonic gradient speeds using a dual-axis head insert gradient at 7T
Motivation: MRSI offers metabolic insights but suffers from long scan times, even at low resolutions. Techniques like EPSI are noisy and require multiple interleaves at 7T, limiting clinical feasibility. Goal(s): Bring MRSI resolution and scan times closer to traditional imaging, without compromising spectral quality or patient comfort. Approach: Silent encoding at 20 kHz using a dual-axis gradient accelerated 3D-FID-CSI (3.5×3.5×5 mm³) from 3h50min to 10min, validated with 7T scans, field camera, B0, and sound measurements. Results: A series of novel technical improvements that demonstrate fast and high-resolution MRSI, without any of the typical trade-offs. Impact: Ultrasonic encoding offers a paradigm shift in MRSI, bringing resolutions and scan times closer to imaging techniques. All without the typical trade-offs: preserving spectral bandwidth, while maintaining patient comfort by lacking gradient noise - paving the way for practical, high-resolution MRSI.
Authors
- Wout Schuth
- Jeroen C.W. Siero (ORCID: https://orcid.org/0000-0001-5079-2868)
- Dennis W. J. Klomp (ORCID: https://orcid.org/0000-0002-5884-5386)
- Jannie P. Wijnen (ORCID: https://orcid.org/0000-0003-2352-3667)
- Mark Gosselink (ORCID: https://orcid.org/0000-0003-1578-3696)
- Dimitri Welting
- Matthias Wienke (ORCID: https://orcid.org/0000-0002-3359-1084)
- Martino Borgo
- Hans Hoogduin (ORCID: https://orcid.org/0000-0001-7707-0750)
- Thomas Roos (ORCID: https://orcid.org/0000-0002-3465-7794)
- Edwin Versteeg (ORCID: https://orcid.org/0000-0003-3235-3970)
- Joost van Straalen
- Martijn Heintges
- Kyung Min Nam (ORCID: https://orcid.org/0000-0002-9185-3986)
- Michael McGrory (ORCID: https://orcid.org/0009-0008-1364-6595)
- Tom Delicaat
- Max Bensink
- Bas de Witte
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/2582
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00