Optimizing of Flourine-19 at 7T MRI in large animal model after Acute Myocardial infarction.
Motivation: Fluorine MRI has been used to track the fate of immune cells , as well as raised widespread interest in the clinical setting. However, 19F MRI signal at ultra-high-field (UHF) has poor detection sensitivity compared to other imaging modalities. Goal(s): Nevertheless, its exact contribution to this process has not yet been investigated at 7T MRI with a large animal model. Approach: To address this, we investigated 19F MRI on Phantoms and in a large animal model of AMI at UHF MRI. Results: Our results suggest a TruFISP sequence and its rapid acquisition time as beneficial for 19F MRI signal detection in the targeted regions. Impact: The present work represents an MRI approach to test time and intensity of 19F signal i (ex vivo & in vivo) in large animal after AMI.
Authors
- Wolfgang R. Bauer (ORCID: https://orcid.org/0000-0002-4652-7313)
- Mahmoud Abd El Hamid (ORCID: https://orcid.org/0000-0003-0969-9543)
- Marzieh Keshtkar
- Anna Frey (ORCID: https://orcid.org/0000-0002-2955-6753)
- Ibrahim A. Elabyad (ORCID: https://orcid.org/0000-0002-0408-2942)
- Ulrich Hofmann (ORCID: https://orcid.org/0000-0002-3681-2073)
- Maxim Terekhov (ORCID: https://orcid.org/0000-0001-5617-7751)
- Sofia Dembski (ORCID: https://orcid.org/0000-0003-0427-1644)
- Wolfgang Schreiber (ORCID: https://orcid.org/0000-0002-8827-1838)
- G. Ulm
- Anja Stadtmüller (ORCID: https://orcid.org/0009-0008-2854-2027)
- Rebekka Grampp
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/3070
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00