Association of Iron Level in the Nucleus Accumbens with Cognitive Impairment in Preeclampsia
Motivation: This study aims to investigate alterations in susceptibility values obtained from quantitative susceptibility mapping (QSM) of the striatum in patients with preeclampsia, focusing on the correlation between these alterations and cognitive impairment. Goal(s): The objective is to clarify the relationship between susceptibility values and cognitive impairment in preeclampsia patients, as well as to explore the associated contributing factors. Approach: Prospective cohort study Results: Our study revealed higher susceptibility values of nucleus accumbens(NAc) in preeclampsia patients. A correlation between the susceptibility values and a decline in executive function was observed. Impact: This study introduces a novel indicator that utilizes QSM techniques for early prediction of preeclampsia and associated cognitive impairment, potentially improving diagnostic accuracy and intervention strategies.
Authors
- Lingfei Guo (ORCID: https://orcid.org/0000-0002-4885-625X)
- Xinyue Zhang (ORCID: https://orcid.org/0000-0003-1643-608X)
- Zhenyu Cheng (ORCID: https://orcid.org/0009-0000-0717-3228)
- Fushuai Zhang (ORCID: https://orcid.org/0009-0009-5833-4285)
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0003-4987-3892)
- Tao Chen (ORCID: https://orcid.org/0000-0002-1797-0359)
- Yiwen Chen (ORCID: https://orcid.org/0000-0002-7706-7540)
- Meng Li (ORCID: https://orcid.org/0000-0003-2123-2444)
- Na Wang (ORCID: https://orcid.org/0000-0001-9552-0524)
- Linfeng Yang (ORCID: https://orcid.org/0000-0002-3986-5533)
- Pengcheng Liang (ORCID: https://orcid.org/0009-0007-7392-2566)
- Xinxin Huo (ORCID: https://orcid.org/0009-0007-9454-6424)
- Boyao Chen (ORCID: https://orcid.org/0009-0004-6089-7160)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/3163
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00