Undercooked PASTA: Tractometry at low field and low SAR

Motivation: Tractography affords advantage over volumetric segmentation as it separates areas of otherwise homogeneous contrast based on microstructural measures. Tract-based parameter mapping performed at ultra-low-field extends the utility of parametric maps to isolate functional regions, permitting quantitative studies in otherwise unscanned populations Goal(s): We sought to implement a feasible tractometry scheme investigating multiple contrasts on a 0.064T commercial MR system Approach: Corrected and denoised DWIs alongside quantitative T2 (qT2) maps were collected and processed to produce tract-specific measures of several diffusion parameters and qT2. Results: Streamline parameter maps were found to agree with literature values of T2, MD and FA in a healthy participant. Impact: Ultra-low-field MR systems offer unprecedented opportunity to access populations otherwise excluded from scanning by location or means. This work demonstrates that traditional high-field tractometry is possible at 0.064T within a feasible scan duration in healthy adults