Detection of Neuronal Firings in Motor Cortex of Humans under a Task of Finger-Tapping via Quantum-Sensing MRI
Motivation: Functional MRI techniques such as DIANA have been controversial in direct detection of neuronal electrical activities (firings) due to tiny difference between task vs. resting state. Quantum-sensing (qs) MRI is an emerging non-BOLD fMRI technique that has the potential for the direct detection. Goal(s): To explore whether qsMRI detects neuronal firings during a task of finger-tapping. Approach: A group of healthy subjects (age 27-84 years) was studied on a 3T MRI scanner. Results: The qsMRI was able to detect firings, with older people showing higher firing rate during tapping than resting. Impact: This positive outcome will encourage researchers to use the qsMRI in a wide range of studies on brain functions and neurological disorders including normal aging and Alzheimer's disease.
Authors
- Arjun V. Masurkar (ORCID: https://orcid.org/0000-0002-2498-2059)
- Yvonne W. Lui (ORCID: https://orcid.org/0000-0002-9984-9164)
- Yulin Ge (ORCID: https://orcid.org/0000-0002-2320-6031)
- Ying‐Chia Lin (ORCID: https://orcid.org/0000-0001-7243-0980)
- Simon Henin (ORCID: https://orcid.org/0000-0003-0997-3266)
- Yongxian Qian (ORCID: https://orcid.org/0000-0002-9931-7790)
- Anli Liu (ORCID: https://orcid.org/0000-0002-1118-981X)
- Nahbila‐Malikha Kumbella
- Kaitlen M. Watson
- Xingye Chen
- Justin Quimbo
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/3734
- Primary Topic
- EEG and Brain-Computer Interfaces
- Type
- article
- Field-Weighted Citation Impact
- 0.00