Precision neuroimaging and connectomics: individual human brain at ultra-high fields
Motivation: Traditional MRI methods often includes averaging data from brief scanning sessions, which limits specificity and reliability. Goal(s): Our goal is to improve understanding of brain structure-function relationships in the individual human brain. Approach: We used 7 Tesla MRI to scan 10 healthy participants over three sessions (4.5 h of scan time/subject). We derived measures of anatomy, microstructure and multi-state functional MRI, to capture brain network interactions and reconfigurations during rest, memory tasks and movie-watching. Results: We release the multimodal Precision Neuroimaging and Connectomics (PNI) dataset for open research. Impact: Our PNI dataset offers openly accessible, ultra-high resolution 7T MRI data across multiple sessions, enabling researchers to explore structure-function relationships in the brain with unprecedented detail and supporting reproducible neuroscience research.
Authors
- Boris C. Bernhardt (ORCID: https://orcid.org/0000-0001-9256-6041)
- Nicole Eichert (ORCID: https://orcid.org/0000-0001-7818-5787)
- Oualid Benkarim (ORCID: https://orcid.org/0000-0003-3922-7643)
- Sofie Louise Valk (ORCID: https://orcid.org/0000-0003-2998-6849)
- Casey Paquola (ORCID: https://orcid.org/0000-0002-0190-4103)
- Raúl Rodríguez‐Cruces (ORCID: https://orcid.org/0000-0002-2917-1212)
- Jessica Royer (ORCID: https://orcid.org/0000-0002-4448-8998)
- Christine Tardif (ORCID: https://orcid.org/0000-0001-8356-6808)
- Jordan DeKraker (ORCID: https://orcid.org/0000-0002-4093-0582)
- Donna Gift Cabalo (ORCID: https://orcid.org/0000-0001-9568-1723)
- Shahin Tavakol (ORCID: https://orcid.org/0000-0002-7585-8963)
- Youngeun Hwang (ORCID: https://orcid.org/0000-0002-6921-0423)
- Yezhou Wang (ORCID: https://orcid.org/0000-0003-3650-5476)
- Valeria Kebets (ORCID: https://orcid.org/0000-0003-1707-7437)
- David A. Rudko (ORCID: https://orcid.org/0000-0002-1299-954X)
- Jonathan Smallwood (ORCID: https://orcid.org/0000-0002-7298-2459)
- Ilana R. Leppert (ORCID: https://orcid.org/0000-0001-7672-0918)
- Risa Thevakumaran
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/3346
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00