Motion corrected MP2RAGE neonatal imaging at ultra-high field with inline reconstruction.
Motivation: Traditionally acquired 3D MP2RAGE datasets are liable to motion artefacts due to long scan times. This is exacerbated in neonatal scanning when motion is involuntary and unpredictable. Goal(s): Combine an optimized MP2RAGE 7T neonatal protocol with DISORDER joint motion estimation and image reconstruction and implement Gadgetron inline reconstruction. Approach: A neonatal cohort was scanned at 7T using our motion corrected MP2RAGE acquisition. Reconstructions were processed offline or inline before qualitative and quantitative assessment of image quality. Results: Images after motion correction are sharper and show reduction in image artefacts across all 18 datasets. Quantitative metrics and radiologist scores are improved with statistical significance. Impact: DISORDER acquisition and reconstruction significantly improves the quality of T1w neonatal imaging at 7T using MP2RAGE, as indicated by both quantitative metrics and radiological scoring. Deployment of Gadgetron-based inline DISORDER reconstruction enables scanner preview of the motion corrected 3D volumes.
Authors
- Daniel W. D. West (ORCID: https://orcid.org/0000-0001-9195-2602)
- Lucilio Cordero‐Grande (ORCID: https://orcid.org/0000-0003-1477-304X)
- Alexandra F. Bonthrone (ORCID: https://orcid.org/0000-0001-5487-5564)
- Sharon Giles (ORCID: https://orcid.org/0000-0002-8528-3745)
- Shaihan Malik (ORCID: https://orcid.org/0000-0001-8925-9032)
- Carla Costa (ORCID: https://orcid.org/0000-0002-0027-8462)
- Sarah McElroy (ORCID: https://orcid.org/0000-0002-4271-5931)
- Yannick Brackenier (ORCID: https://orcid.org/0000-0002-9210-5939)
- Davide Gallo
- Jon O. Cleary (ORCID: https://orcid.org/0000-0001-8836-9934)
- Tomoki Arichi (ORCID: https://orcid.org/0000-0002-3550-1644)
- Philippa Bridgen (ORCID: https://orcid.org/0009-0008-8051-8139)
- Zihan Ning (ORCID: https://orcid.org/0000-0002-9692-1976)
- Joseph V. Hajnal (ORCID: https://orcid.org/0000-0002-2690-5495)
- Raphaël Tomi‐Tricot (ORCID: https://orcid.org/0000-0002-6149-9154)
- Pierluigi Di Ciò (ORCID: https://orcid.org/0000-0002-0457-9449)
- Ayse Sila Dokumaci
- Ines Tomazinho
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/0339
- Primary Topic
- Atomic and Subatomic Physics Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00