Self-Improved Multi-Shot Abdominal Diffusion-Weighted Imaging: A Motion-Resolved High-Resolution Solution

Motivation: Successful neural high-resolution DWI methods are limited for abdominal imaging due to severe respiratory motion, cardiac pulsations, and intestinal peristalsis, which cause ghosting, misregistration, blurring, and signal attenuation. Goal(s): We propose a motion-resolved, self-adaptive solution for high-resolution abdominal DWI. Approach: The novel motion correction solution for multi-shot high-resolution abdominal DWI, called MoCo-mDWI, combines an adaptive motion-resolved acquisition with self-improvement preparation and DL-based motion deblurring. Results: Preliminary results showed that MoCo-mDWI significantly outperformed traditional multi-shot and single-shot DWI techniques in ghost-to-signal ratio (GSR) and overall image quality. Impact: The proposed solution enables in-vivo high-resolution abdominal DWI in clinical practice.