Free-breathing respiratory-resolved 3D Lung Vasculature MRI at 0.55T with non-rigid motion-corrected reconstruction

Motivation: To leverage low-field MRI to achieve high quality 3D respiratory-resolved lung vasculature imaging, to improve diagnostic capabilities across respiratory phases. Goal(s): To develop a free-breathing respiratory-resolved 3D lung imaging framework with feasible scan time at 0.55T. Approach: Data was acquired in 6 healthy subjects on a 0.55T scanner, with three sequences: a bright-blood bSSFP sequence (CMRA), an interleaved bright and black-blood bSSFP sequence (BOOST), and a Proton Density sequence. Results: A respiratory-resolved reconstruction framework is demonstrated for 6 healthy volunteers acquired with three sequences. The lung vessels and other anatomical structures are clearly delineated across the respiratory phases, from inspiration to end expiration. Impact: 3D respiratory-resolved lung images at 0.55T may enable diagnostic capabilities across respiratory phases.