Placental contractions in healthy and compromised placentas
Motivation: Placental contractions will have an impact on the blood flow through the placenta and therefore the health of the fetus. However they have not been fully characterised and have never been studied in compromised pregnancies. Goal(s): Characterise contractions in healthy placentas and compare to compromised pregnancies. Approach: Dynamic respiratory triggered EPI for 10-30 minutes to measure changes in placental shape and BOLD signal. Results: All groups displayed placental contractions and differences in the depth and length of contractions was observed in compromised pregnancies. Impact: A third of stillbirths are caused by placental complications. Placental contractions are a newly identified physiological phenomenon and so it is important to understand any role they may play in compromised pregnancies.
Authors
- Ruizhe Li (ORCID: https://orcid.org/0000-0003-2512-845X)
- Neele Dellschaft (ORCID: https://orcid.org/0000-0001-5483-1684)
- Craig Platt
- Christopher R. Bradley (ORCID: https://orcid.org/0000-0002-2174-2279)
- Grazziela Patrocinio Figueredo (ORCID: https://orcid.org/0000-0003-4094-7680)
- Nia Jones (ORCID: https://orcid.org/0000-0003-0793-0967)
- George Hutchinson (ORCID: https://orcid.org/0000-0002-8069-9821)
- Kate Walker (ORCID: https://orcid.org/0000-0001-5392-6323)
- Penny Anne Gowland (ORCID: https://orcid.org/0000-0002-4900-4817)
- Xin Chen (ORCID: https://orcid.org/0000-0002-5310-5426)
- Amy Turnbull
- Louise Dewick
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/0167
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00