Design and development of a transmit RF coil for large field of view hyperpolarized 13C imaging

Motivation: To bring hyperpolarized 13C body imaging to its full potential. Goal(s): Develop a 13C transmit coil that can provide large FOV coverage with uniform B1+ field, while minimizing impact to patient access and comfort. Approach: An asymmetric 8 rung high-pass birdcage coil was designed to sit directly on the patient cradle. The prototype coil was constructed as a flat base along with a detachable top cage. Results: The B1 maps acquired using the 13C birdcage coil in T/R mode showed good uniformity. The coil also performed as expected as a Tx only coil. Impact: The 13C transmit coil developed in this project provides uniform RF excitation across a large FOV without compromising patient comfort and the 1H imaging. It will be an integral element for routine clinical HP 13C metabolic imaging in the future.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2025-09-16
DOI
https://doi.org/10.58530/2025/4477
Primary Topic
Advanced NMR Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Design and development of a transmit RF coil for large field of view hyperpolarized 13C imaging

Kayvan R. Keshari, Jana Vincent, Charles H. Cunningham, Arnaud Comment et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Advanced NMR Techniques and Applications
article

Design and development of a transmit RF coil for large field of view hyperpolarized 13C imaging

Kayvan R. Keshari, Jana Vincent, Charles H. Cunningham, Arnaud Comment, D. Chris Anderson, Justin Y. C. Lau, Atsushi Nozaki, Thomas Grafendorfer, Fraser Robb, Thomas Stickle, Victor Taracila, Tony Thomas, Albert Chen, Takashi Ishiguro, Edward Baus, Venkata Rao Malasani
article en

Abstract

Motivation: To bring hyperpolarized 13C body imaging to its full potential. Goal(s): Develop a 13C transmit coil that can provide large FOV coverage with uniform B1+ field, while minimizing impact to patient access and comfort. Approach: An asymmetric 8 rung high-pass birdcage coil was designed to sit directly on the patient cradle. The prototype coil was constructed as a flat base along with a detachable top cage. Results: The B1 maps acquired using the 13C birdcage coil in T/R mode showed good uniformity. The coil also performed as expected as a Tx only coil. Impact: The 13C transmit coil developed in this project provides uniform RF excitation across a large FOV without compromising patient comfort and the 1H imaging. It will be an integral element for routine clinical HP 13C metabolic imaging in the future.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 77%
Advanced NMR Techniques and Applications
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Design and development of a transmit RF coil for large field of view hyperpolarized 13C imaging — Kayvan R. Keshari, Jana Vincent, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2025) | TGRS Research Map | TGRS