Fourier Informed Native Deblurring (FIND): A Robust Solution for Blurring in pseudo-Continuous Arterial Spin Labeling (pCASL) MRI

Motivation: The low resolution of pCASL MRI leads to blurring effects that hinder brain tissue differentiation and reduce diagnostic accuracy, highlighting the need for an effective deblurring solution. Goal(s): Develop FIND (Fourier Informed Native Deblurring), a method to restore high-frequency image details missing in pCASL MRI acquisitions. Approach: FIND uses a Fourier-based deblurring filter calculated from a reference image to correct blurring artifacts in pCASL MRI. Results: FIND achieves significant improvements in image clarity, tissue contrast, and diagnostic precision in brain imaging. Impact: FIND improves pCASL MRI image quality, enabling a more accurate assessment of brain pathologies and advancing clinical imaging applications.