Towards a hybrid low-cost MR-PET technology with therapeutic ultrasound capabilities.
Motivation: Hybrid medical devices can enhance diagnostic and therapeutic applications but are typically costly, large and inaccessible. Goal(s): To develop a trimodal MR-PET-FUS system utilizing low-field MRI for a more affordable, accessible solution. Approach: We integrated a 72 mT Halbach MRI scanner with PET and FUS technologies. We worked with a cylindrical phantom containing a copper-sulphate solution, gelatin, and a radioactive tracer. The system uses PET and MRI for imaging and FUS for heating. Results: We have achieved simultaneous MR-PET imaging and successfully heated the phantom with FUS, demonstrating low-field MRI compatibility in a trimodal setup. Impact: We present the first low-field MRI-integrated trimodal MR-PET-FUS system, enabling affordable, accessible devices. Having demonstrated simultaneous MR-PET acquisition and FUS heating, this work opens the path for cost-effective, multimodal diagnostics and treatment applications.
Authors
- Antonio J. González (ORCID: https://orcid.org/0000-0001-6742-5626)
- Eduardo Pallás (ORCID: https://orcid.org/0000-0001-7791-6592)
- Santiago Jiménez-Serrano (ORCID: https://orcid.org/0000-0003-2917-6053)
- María José Rodríguez-Álvarez (ORCID: https://orcid.org/0000-0001-8333-8792)
- Joseba Alonso (ORCID: https://orcid.org/0000-0002-2721-1380)
- José Miguel Algarín (ORCID: https://orcid.org/0000-0003-2644-7225)
- Rubén Bosch (ORCID: https://orcid.org/0000-0002-7316-7819)
- Francisco Camarena (ORCID: https://orcid.org/0000-0002-6713-1414)
- Carlos Alfonso (ORCID: https://orcid.org/0000-0002-2378-021X)
- Alicia Carrión (ORCID: https://orcid.org/0000-0002-0630-6065)
- Andrea Gonzalez‐Montoro (ORCID: https://orcid.org/0000-0002-7319-4278)
- Juan J. García (ORCID: https://orcid.org/0000-0001-7821-9502)
- Teresa Guallart‐Naval
- Diana Andrés (ORCID: https://orcid.org/0000-0002-7588-6155)
- Marta Freire (ORCID: https://orcid.org/0000-0002-1150-383X)
- J. Benlloch (ORCID: https://orcid.org/0000-0001-6073-1436)
- Fernando López (ORCID: https://orcid.org/0000-0003-2029-5945)
- J. L. Alonso-Ramos
- Koldo Vidal
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/1518
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00