TraceOrg: An AI Platform for Reproducible ADPKD Organ/Cyst Contouring on MRI
Motivation: Abdominal organ volumes are critical MRI biomarkers in many diseases, including autosomal dominant polycystic kidney disease. Goal(s): To develop an internet accessible, kidney/liver/cyst volume measurement tool. Approach: 3D Unet transformer hybrid model internet based calculator for kidney liver and renal cysts uploads DICOM MRimages with automatic anonymization performed in the browser software to ensure HIPAA compliance. External validation: 153 MRIs from another country (coronal T2 fatsat, and T1 breathhold sequences). Results: TraceOrg demonstrated high Dice, low Average Symmetric Surface Distance, low Hausdorff Distance for kidney, liver and renal cyst segmentation compared to manual expert ground truth segmentation. Impact: TraceOrg provides accurate and efficient segmentations for measuring kidney liver and renal cyst volumes to enhance radiologist subjective assessments of ADPKD abdominal MRI and is readily accessible via internet.
Authors
- Elisa Scalco (ORCID: https://orcid.org/0000-0003-2721-5792)
- Anna Caroli (ORCID: https://orcid.org/0000-0002-4130-4663)
- Mert R. Sabuncu (ORCID: https://orcid.org/0000-0002-7068-719X)
- Martin R. Prince (ORCID: https://orcid.org/0000-0002-9883-0584)
- Hreedi Dev (ORCID: https://orcid.org/0000-0002-5341-8350)
- Federico Lussana (ORCID: https://orcid.org/0000-0002-6510-8616)
- Zhongxiu Hu (ORCID: https://orcid.org/0009-0009-9258-5459)
- Kurt Teichman (ORCID: https://orcid.org/0000-0002-5122-7067)
- Yelynn Kim
- Xinzi He (ORCID: https://orcid.org/0000-0003-4492-7695)
- Giulia Villa (ORCID: https://orcid.org/0000-0003-1120-9638)
- Chenglin Zhu (ORCID: https://orcid.org/0009-0003-6662-4908)
- Qing Xiong (ORCID: https://orcid.org/0009-0006-7305-2372)
- Siria Pasini (ORCID: https://orcid.org/0009-0009-6879-3805)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/5114
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00