Wireless EEG System for Concurrent TMS-EEG-fMRI

Motivation: We present a novel approach to challenges posed by concurrent TMS-EEG-fMRI systems, using a wireless EEG system based on the Single Chip Micro Mote (SCμM). Goal(s): This approach could enable safer, more effective multimodal brain imaging and stimulation studies by eliminating long wires and large loop areas in the MRI environment. Approach: We demonstrate a prototype using SCμM-3C with Texas Instruments ADS1299 on an MRI-safe PCB. Results: Our results show stable operation and communication from within the bore with minimal disruption from structural and functional MRI sequences. Ongoing work aims to miniaturize the system by integrating a custom EEG front-end onto SCμM. Impact: This wireless EEG system aims to advance multimodal neuroimaging by enabling concurrent TMS-EEG-fMRI studies with reduced interference and improved safety. The system may improve the many relevant diagnostic and therapeutic applications in neuroscience. The presented prototype is made open-source.