Multi-center and multi-vendor reproducibility of PCASL data on 3T MRI scanners
Motivation: Facilitating reliable multi-center renal perfusion MRI studies Goal(s): Assessing multi-center and multi-vendor reproducibility of perfusion biomarkers on 3T scanners from 2 clinical centers. Approach: Thirty-nine healthy volunteers were scanned in two vendors in separate days. MRI protocol included a PCASL sequence harmonized between vendors. Renal blood flow (RBF) maps were generated for each subject/scan. Bland-Altman plots, ICC and CVws were assesed. Results: Reproducibility of ASL was good for the two vendors. In addition, they showed comparable results in terms of RBF values. These findings provide evidence in favor of the need of ASL harmonization across vendors to allow reliable multi-center perfusion MRI studies. Impact: Harmonized PCASL sequence for renal perfusion measurements shows promise for reliable multi-center and multi-vendor studies
Authors
- Anika Strittmatter (ORCID: https://orcid.org/0000-0002-6184-8481)
- Matias Trillini (ORCID: https://orcid.org/0000-0003-1859-1729)
- Rebeca Echeverría‐Chasco (ORCID: https://orcid.org/0000-0003-0199-2593)
- María A. Fernández‐Seara (ORCID: https://orcid.org/0000-0001-8536-6295)
- Steffen Ringgaard (ORCID: https://orcid.org/0000-0001-5353-7379)
- Anna Caroli (ORCID: https://orcid.org/0000-0002-4130-4663)
- Lucian-Mihai Itu
- Michela Bozzetto (ORCID: https://orcid.org/0000-0002-2045-5550)
- Susan Francis (ORCID: https://orcid.org/0000-0003-0903-7507)
- Nuria Garcı́a-Fernández (ORCID: https://orcid.org/0000-0003-1082-0806)
- Anish Raj (ORCID: https://orcid.org/0000-0003-0036-0228)
- José María Mora‐Gutiérrez (ORCID: https://orcid.org/0000-0001-8537-5394)
- Esben Søvsø Szocska Hansen (ORCID: https://orcid.org/0000-0001-5512-9870)
- Verónica Aramendía‐Vidaurreta (ORCID: https://orcid.org/0000-0001-9834-2866)
- David C. Alsop (ORCID: https://orcid.org/0000-0002-8206-1995)
- Niels Henrik Buus (ORCID: https://orcid.org/0000-0001-7972-8181)
- Christoffer Laustsen (ORCID: https://orcid.org/0000-0002-0317-2911)
- Manuel Taso (ORCID: https://orcid.org/0000-0003-2405-9165)
- Marta Vidorreta (ORCID: https://orcid.org/0000-0002-4272-3691)
- Larisa Micu
- Leyre García-Ruiz (ORCID: https://orcid.org/0000-0002-2019-2885)
- Giulia Villa (ORCID: https://orcid.org/0000-0003-1120-9638)
- Paolo Brambilla (ORCID: https://orcid.org/0000-0002-6809-1178)
- Malene Aastrup (ORCID: https://orcid.org/0009-0005-0728-3167)
- Siria Pasini (ORCID: https://orcid.org/0009-0009-6879-3805)
- Frank G. Zoellner
- Tau Vendelboe
- Iona Urdea
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/4772
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00