Multi-site use of a vendor-agnostic, open-source protocol (VOP) framework to validate and share open-source pulse sequences

Motivation: A community-driven vendor-agnostic, open-source protocols (VOP) framework will expand the acquisition of reproducible MR data by collaboratively, safely, effectively, and ethically sharing magnetic resonance (MR) protocols. Goal(s): To validate and share two Pypulseq and GammaStar generated pulse sequences at multiple sites and two field strengths Approach: We acquired T1w, T2w, and quantitative relaxometric data from six sites on the Siemens, Philips, and the mri4all Zeugmatron1 platforms; sharing the code, data, images and documentation; compliant with the framework requisites Results: The sites fulfilled the requirements of the framework, and sites performing qMR provided similar and accurate T1 and T2 measures on the respective phantoms Impact: We demonstrated the expanded use of the VOP framework to validate and share the IRSE and TSE sequences across sites, vendors, software versions, and two field strengths. This framework created an online platform to interact and share pulse sequences.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2025-09-16
DOI
https://doi.org/10.58530/2025/1971
Primary Topic
Particle accelerators and beam dynamics
Type
article
Field-Weighted Citation Impact
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article

Multi-site use of a vendor-agnostic, open-source protocol (VOP) framework to validate and share open-source pulse sequences

Sairam Geethanath, Jon‐Fredrik Nielsen, Kai Tobias Block, Mojtaba Shafiekhani et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Particle accelerators and beam dynamics
article

Multi-site use of a vendor-agnostic, open-source protocol (VOP) framework to validate and share open-source pulse sequences

Sairam Geethanath, Jon‐Fredrik Nielsen, Kai Tobias Block, Mojtaba Shafiekhani, William A. Grissom, Simon Konstandin, Qingping Chen, Amaresha Shridhar Konar, Daniel Hoinkiss, Maxim Zaitsev, Anaïs Artiges, John Vaughan, Rita G. Nunes, Sandeep Ganji, Tiago Fernandes, Martijn Nagtegaal, Vasco Mascarenhas
article en

Abstract

Motivation: A community-driven vendor-agnostic, open-source protocols (VOP) framework will expand the acquisition of reproducible MR data by collaboratively, safely, effectively, and ethically sharing magnetic resonance (MR) protocols. Goal(s): To validate and share two Pypulseq and GammaStar generated pulse sequences at multiple sites and two field strengths Approach: We acquired T1w, T2w, and quantitative relaxometric data from six sites on the Siemens, Philips, and the mri4all Zeugmatron1 platforms; sharing the code, data, images and documentation; compliant with the framework requisites Results: The sites fulfilled the requirements of the framework, and sites performing qMR provided similar and accurate T1 and T2 measures on the respective phantoms Impact: We demonstrated the expanded use of the VOP framework to validate and share the IRSE and TSE sequences across sites, vendors, software versions, and two field strengths. This framework created an online platform to interact and share pulse sequences.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 67%
Particle accelerators and beam dynamics
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