Quantitative study of R2 'Mapping to evaluate the effect of remote ischemic preconditioning

Motivation: Remote ischemic preconditioning can reduce renal IRI injury. There is still a lack of a noninvasive and accurate index to evaluate the effect of RIPC in clinical practice. Goal(s): To evaluate the effect of R2-mapping imaging on remote ischemic preconditioning Approach: The RIPC model of both lower limbs of experimental rabbits was established, and MRI imaging, hematological detection, renal oxidation and antioxidant indexes were detected respectively 1h and 24h after RIPC Results: Compared with the control group, the R2 'value of renal medulla in RIPC group was significantly decreased, pO2 and sO2 were increased, SOD activity was increased, and MDA content was decreased. Impact: To provide a non-invasive MRI technique for quantitative evaluation of RIPC effect in clinic