Prescribed opioid analgesic use in pregnancy and risk of neurodevelopmental disorders in children: A retrospective study in Sweden
While increased risks with high amounts of POA exposure cannot be ruled out, the results suggest that confounding may largely explain the increased risks of ASD and ADHD associated with prenatal POA exposure at the levels observed in this cohort.
Authors
- Friedericke Fischer (ORCID: https://orcid.org/0009-0005-8655-6505)
- Zheng Chang (ORCID: https://orcid.org/0000-0002-8087-1417)
- Emma N. Cleary (ORCID: https://orcid.org/0000-0001-6929-544X)
- Ayesha C. Sujan (ORCID: https://orcid.org/0000-0002-4374-9949)
- Paul Lichtenstein (ORCID: https://orcid.org/0000-0003-3037-5287)
- Tyra Lagerberg (ORCID: https://orcid.org/0000-0003-2480-0216)
- Anna Sara Öberg (ORCID: https://orcid.org/0000-0001-6638-1895)
- Patrick D. Quinn (ORCID: https://orcid.org/0000-0002-6770-8762)
- Brian Matthew D'Onofrio (ORCID: https://orcid.org/0000-0002-5248-7434)
- Martin E. Rickert (ORCID: https://orcid.org/0000-0002-7010-7300)
Institutions
- Harvard University (US)
- Warneford Hospital (GB)
- Karolinska Institutet (SE)
- University of Oxford (GB)
- Indiana University Bloomington (US)
- Stanford University (US)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1371/journal.pmed.1004721
- Citations
- 1
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 1.88