In vivo T1-mapping using Open-MOLLI in GE scanners

Motivation: The open-source myocardial T1 mapping (Open-MOLLI) sequence allows the application of the same methodology in different settings for improved reproducibility. Goal(s): We aim to test Open-MOLLI, originally developed on a Siemens system, on a GE scanner. Approach: The Open-MOLLI sequence was adapted to a 3T GE vendor system, and was acquired in 2 subjects. T1 of one axial slice of the brain was estimated, and white matter (WM) and grey matter (GM) T1 values were compared with the literature. Results: Open-MOLLI was successfully adapted to the GE system, allowing to estimate T1-values that are consistent with literature values for GM and WM. Impact: The open-source myocardial T1 mapping (Open-MOLLI) was successfully adapted and tested on a GE Signa 3T PET-MR scanner. The sequence is now ready to be applied in inter-scanner reproducibility brain studies. Triggering will be added next for cardiac applications.