Accelerated myocardial T1 mapping at low field

Motivation: Myocardial T1 mapping has been successfully demonstrated at low field (0.55T) but only enable the acquisition of one slice per breathhold. Goal(s): The aim of this study is to develop an accelerated myocardial T1 mapping method at 0.55T. Approach: A modified FAST1 scheme is proposed for 0.55T where 3 slices are acquired in a 12s breathhold, using two inversion-recovery blocks per slice (with 2 images/block) and slice-selective inversion pulses. Results: In comparison to a standard MOLLI sequence, the proposed low-field FAST1 scheme led to an acceleration factor of 3 with similar T1 times and improved T1 precision. Impact: Accelerated myocardial T1 mapping with improved precision will reduce the duration of multi-slice myocardial T1 mapping protocol and may provide increase spatial coverage to existing protocol with limited slice coverage.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2025-09-16
DOI
https://doi.org/10.58530/2025/1829
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
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article

Accelerated myocardial T1 mapping at low field

Alexander Neofytou, Reza Razavi, Karl Kunze, Andrew Tyler et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Cardiac Imaging and Diagnostics
article

Accelerated myocardial T1 mapping at low field

Alexander Neofytou, Reza Razavi, Karl Kunze, Andrew Tyler, Charlotte Rogers, Amedeo Chiribiri, Sébastien Roujol, Li Huang, Charel Junior Mangama Sindzi
article en

Abstract

Motivation: Myocardial T1 mapping has been successfully demonstrated at low field (0.55T) but only enable the acquisition of one slice per breathhold. Goal(s): The aim of this study is to develop an accelerated myocardial T1 mapping method at 0.55T. Approach: A modified FAST1 scheme is proposed for 0.55T where 3 slices are acquired in a 12s breathhold, using two inversion-recovery blocks per slice (with 2 images/block) and slice-selective inversion pulses. Results: In comparison to a standard MOLLI sequence, the proposed low-field FAST1 scheme led to an acceleration factor of 3 with similar T1 times and improved T1 precision. Impact: Accelerated myocardial T1 mapping with improved precision will reduce the duration of multi-slice myocardial T1 mapping protocol and may provide increase spatial coverage to existing protocol with limited slice coverage.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 65%
Cardiac Imaging and Diagnostics
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