The utility of 4D Flow MRI blood flow analysis in patients with cervical carotid artery stenosis
Motivation: Turbulence at the site of carotid artery stenosis is believed to contribute to plaque formation and rupture, but it has not been thoroughly studied in vivo. Goal(s): We aimed to assess and elucidate the characteristics of turbulent kinetic energy (TKE) measurements derived from 4D Flow MRI. Approach: We compared TKE obtained from 4D Flow MRI to conventional clinical markers evaluated by MRI and ultrasonography parameters. Results: TKE measurements demonstrated high inter-rater reliability. Significant correlations were observed between TKE, the degree of stenosis, intima-media thickness (IMT), and plaque intensity. Impact: In cases of carotid artery stenosis, TKE measured by 4D Flow MRI may serve as a parameter for characterizing the pathology of carotid artery stenosis and risk stratification.
Authors
- Masatoki Nakaza (ORCID: https://orcid.org/0000-0001-5750-9498)
- Takahiro Ando (ORCID: https://orcid.org/0000-0001-6673-3504)
- Tetsuro Sekine (ORCID: https://orcid.org/0000-0003-1547-6696)
- Kotomi Iwata (ORCID: https://orcid.org/0000-0003-0406-0388)
- Shin‐ichiro Kumita (ORCID: https://orcid.org/0000-0001-8107-4703)
- Yasuo Murai (ORCID: https://orcid.org/0000-0002-9753-1873)
- Kentaro Suzuki
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/2360
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00