Free-breathing hepatic Oxygen Extraction Fraction (OEF) mapping using radial GESSE
Motivation: Non-invasive hepatic oxygenation mapping has been limited to single slice and single breath-hold. Goal(s): Multi-slice mapping of hepatic oxygenation in free-breathing is needed. Approach: In this study, hepatic oxygen extraction fraction (OEF) was measured using a radial gradient-echo sampling of spin-echo (rGESSE) sequence to cover multiple liver slices and be robust against respiratory motion. For OEF analysis, a feedforward artificial neural network (ANN) was used. Results: This study demonstrates the feasibility of radial GESSE to measure hepatic OEF. Impact: The feasibility of free-breathing liver OEF mapping using rGESSE was investigated. Further improvement of the quantification, possibly using measured macroscopic field inhomogeneities may be needed.
Authors
- Oliver Sedlaczek (ORCID: https://orcid.org/0000-0002-8709-5481)
- Heinz‐Peter Schlemmer (ORCID: https://orcid.org/0000-0002-9291-0954)
- Felix Tobias Kurz (ORCID: https://orcid.org/0000-0001-7616-7147)
- Simon M. F. Triphan (ORCID: https://orcid.org/0000-0003-2068-1184)
- Hans‐Ulrich Kauczor (ORCID: https://orcid.org/0000-0002-6730-9462)
- Mark E. Ladd (ORCID: https://orcid.org/0000-0002-4128-9440)
- Christian H. Ziener (ORCID: https://orcid.org/0000-0001-8854-7358)
- Ke Zhang (ORCID: https://orcid.org/0000-0002-7244-8483)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.58530/2025/2848
- Primary Topic
- Atomic and Subatomic Physics Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00