Effect of Cerebellar tDCS on Postural Control and Neuroplastic Changes in Chronic Ankle Instability

Motivation: We aimed to activate cerebellar functions and evaluate its effect on postural control and associated neuroplastic alternations in chronic ankle instability(CAI). Goal(s): Postural control impairment, a key feature of CAI, is crucial for daily and sports activities but lacks effective treatment strategies. Recent evidence links maladaptive neuroplasticity in the cerebellum to these deficits. Approach: Consecutive CAI participants were assigned to sham or active groups for cerebellar anodal tDCS in a preliminary randomized controlled trial. Results: Our study showed that a single cerebellar tDCS session improved postural control in CAI patients and increased coherence in the cerebellum's superior lobe. Impact: This preliminary study marks the first application of cerebellar tDCS in the rehabilitation of CAI and musculoskeletal injuries.