Application Value of MR Elastography in the Identification of Benign and Malignant Liver Lesions and Prognostic Prediction of Malignant Tumors

Motivation: The differentiation between benign and malignant liver lesions is critical for clinical decision-making, yet traditional methods may not always provide clear distinctions. Goal(s): To evaluate the efficacy of Magnetic Resonance Elastography (MRE) in differentiating benign and malignant liver lesions and to assess its potential in predicting the prognosis of malignant tumors. Approach: Retrospective analysis of 207 liver lesion cases using 2D MRE scans to measure elasticity. Results: Malignant lesions had higher elasticity (AUC 0.843), with a 3.90 kPa cutoff. Post-treatment changes were significant in disease progression. Impact: MRE demonstrates potential as a non-invasive imaging biomarker for distinguishing benign from malignant liver lesions and assessing treatment response in malignant tumors. This could facilitate more informed clinical decisions and improve patient outcomes.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2025-09-16
DOI
https://doi.org/10.58530/2025/2835
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Application Value of MR Elastography in the Identification of Benign and Malignant Liver Lesions and Prognostic Prediction of Malignant Tumors

Wenli Tan, Jiaoyan Wang, Xutong Huang, Jie Yuan et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Liver Disease Diagnosis and Treatment
article

Application Value of MR Elastography in the Identification of Benign and Malignant Liver Lesions and Prognostic Prediction of Malignant Tumors

Wenli Tan, Jiaoyan Wang, Xutong Huang, Jie Yuan, Zhiwei Qin, Sun Yuejun, Wenxin Ma
article en

Abstract

Motivation: The differentiation between benign and malignant liver lesions is critical for clinical decision-making, yet traditional methods may not always provide clear distinctions. Goal(s): To evaluate the efficacy of Magnetic Resonance Elastography (MRE) in differentiating benign and malignant liver lesions and to assess its potential in predicting the prognosis of malignant tumors. Approach: Retrospective analysis of 207 liver lesion cases using 2D MRE scans to measure elasticity. Results: Malignant lesions had higher elasticity (AUC 0.843), with a 3.90 kPa cutoff. Post-treatment changes were significant in disease progression. Impact: MRE demonstrates potential as a non-invasive imaging biomarker for distinguishing benign from malignant liver lesions and assessing treatment response in malignant tumors. This could facilitate more informed clinical decisions and improve patient outcomes.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 66%
Liver Disease Diagnosis and Treatment
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