Isolation of two new isomers of fusarin D from <i>Fusarium</i> sp. G10, an endophytic fungus of <i>Iris japonica</i>

<i>Fusarium</i> species are globally distributed filamentous fungi with a variety of bioactive compounds. Six fusarins (<b>1 - 6</b>), including two new isomers of fusarin D (<b>5</b> and <b>6</b>), along with six known terpenoids (<b>7 </b>-<b> 12</b>), were isolated from the endophytic fungus <i>Fusarium</i> sp. G10, which was derived from <i>Iris japonica</i> Thunb. The structures of all compounds were elucidated using various spectroscopic techniques, and their cytotoxic and antimicrobial activities were assessed. Compounds <b>2</b> and <b>3</b> demonstrated selective inhibitory effects on the DU145 and MDA-MB-231 cell lines, with IC₅₀ values ranging from 17.74 to 36.66 µM. Additionally, compound <b>11</b> demonstrated weak inhibitory activity against bacterial strains, with MIC values of 32 and 64 μg/mL.