Optimizing density of intrathecal contrast at digital subtraction myelography: Evaluation of differing needle characteristics and injection rates in a phantom

Dynamic myelography, performed as digital subtraction myelography or dynamic computed tomography myelography, is crucial in diagnosing intracranial hypotension resulting from a cerebrospinal fluid-venous fistula (CVF). The quality of the myelogram is paramount for accurate diagnosis. Using a phantom, the impact of needle type (Quincke vs. Whitacre), caliber, side-hole position, and rate of injection on the quality of the myelogram was determined. The ideal decubitus myelogram would provide a large volume of a hyperdense contrast within the lateral dependent aspect of the thecal sac, optimally flooding the mouths of the neural foramina and root sleeves where the vast majority of CVFs originate. The results of this study suggest it is exclusively the rate of injection that most predictably dictates the quality of the myelogram in this regard. Specifically, a slow injection rate, on the order of 0.1 mL/s, should be opted for to decrease turbulence, optimize myelogram quality, and thus improve CVF detection in clinical practice.

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Publication Details

Journal
Interventional Neuroradiology
Published
2025-09-16
DOI
https://doi.org/10.1177/15910199251375541
Primary Topic
Neurosurgical Procedures and Complications
Type
article
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article

Optimizing density of intrathecal contrast at digital subtraction myelography: Evaluation of differing needle characteristics and injection rates in a phantom

Richard Farb, Anahita Malvea, Emily Chung, Mehran Nasralla et al.
Interventional Neuroradiology
Neurosurgical Procedures and Complications
article

Optimizing density of intrathecal contrast at digital subtraction myelography: Evaluation of differing needle characteristics and injection rates in a phantom

Richard Farb, Anahita Malvea, Emily Chung, Mehran Nasralla, Eef Jacobus Hendriks
article en

Abstract

Dynamic myelography, performed as digital subtraction myelography or dynamic computed tomography myelography, is crucial in diagnosing intracranial hypotension resulting from a cerebrospinal fluid-venous fistula (CVF). The quality of the myelogram is paramount for accurate diagnosis. Using a phantom, the impact of needle type (Quincke vs. Whitacre), caliber, side-hole position, and rate of injection on the quality of the myelogram was determined. The ideal decubitus myelogram would provide a large volume of a hyperdense contrast within the lateral dependent aspect of the thecal sac, optimally flooding the mouths of the neural foramina and root sleeves where the vast majority of CVFs originate. The results of this study suggest it is exclusively the rate of injection that most predictably dictates the quality of the myelogram in this regard. Specifically, a slow injection rate, on the order of 0.1 mL/s, should be opted for to decrease turbulence, optimize myelogram quality, and thus improve CVF detection in clinical practice.

Interventional Neuroradiology
University of Toronto (CA)
Openalex Percentile: Top 64%
Neurosurgical Procedures and Complications
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