Neural Polar Decoders for DNA Data Storage

Synchronization errors, arising from both synthesis and sequencing noise, present a fundamental challenge in DNA-based data storage systems. These errors are often modeled as insertion-deletion-substitution (IDS) channels, for which maximum-likelihood decoding is quite computationally expensive. In this work, we propose a data-driven approach based on neural polar decoders (NPDs) to design decoders with reduced complexity for channels with synchronization errors. The proposed architecture enables decoding over IDS channels with reduced complexity <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">O</i>(<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">AN</i> log<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</i>), where <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">A</i> is a tunable parameter independent of the channel. NPDs require only sample access to the channel and can be trained without an explicit channel model. Additionally, NPDs provide mutual information (MI) estimates that can be used to optimize input distributions and code design. We demonstrate the effectiveness of NPDs on both synthetic deletion and IDS channels. For deletion channels, we show that NPDs achieve near-optimal decoding performance and accurate MI estimation, with significantly lower complexity than trellis-based decoders. We also provide numerical estimates of the channel capacity for the deletion channel. We extend our evaluation to realistic DNA storage settings, including channels with multiple noisy reads and real-world Nanopore sequencing data. Our results show that NPDs match or surpass the performance of existing methods while using significantly fewer parameters than the state-of-the-art. These findings highlight the promise of NPDs for robust and efficient decoding in DNA data storage systems.

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Publication Details

Journal
IEEE Journal on Selected Areas in Information Theory
Published
2025-01-01
DOI
https://doi.org/10.1109/jsait.2025.3610751
Citations
1
Primary Topic
DNA and Biological Computing
Type
article
Field-Weighted Citation Impact
0.81
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article

Neural Polar Decoders for DNA Data Storage

Ziv Aharoni, Henry D. Pfister
1 citations
IEEE Journal on Selected Areas in Information Theory
DNA and Biological Computing
0.81
article

Neural Polar Decoders for DNA Data Storage

Ziv Aharoni, Henry D. Pfister
article en
1 citations

Abstract

Synchronization errors, arising from both synthesis and sequencing noise, present a fundamental challenge in DNA-based data storage systems. These errors are often modeled as insertion-deletion-substitution (IDS) channels, for which maximum-likelihood decoding is quite computationally expensive. In this work, we propose a data-driven approach based on neural polar decoders (NPDs) to design decoders with reduced complexity for channels with synchronization errors. The proposed architecture enables decoding over IDS channels with reduced complexity <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">O</i>(<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">AN</i> log<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</i>), where <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">A</i> is a tunable parameter independent of the channel. NPDs require only sample access to the channel and can be trained without an explicit channel model. Additionally, NPDs provide mutual information (MI) estimates that can be used to optimize input distributions and code design. We demonstrate the effectiveness of NPDs on both synthetic deletion and IDS channels. For deletion channels, we show that NPDs achieve near-optimal decoding performance and accurate MI estimation, with significantly lower complexity than trellis-based decoders. We also provide numerical estimates of the channel capacity for the deletion channel. We extend our evaluation to realistic DNA storage settings, including channels with multiple noisy reads and real-world Nanopore sequencing data. Our results show that NPDs match or surpass the performance of existing methods while using significantly fewer parameters than the state-of-the-art. These findings highlight the promise of NPDs for robust and efficient decoding in DNA data storage systems.

IEEE Journal on Selected Areas in Information TheoryVol. 6
Duke University (US)
Openalex Percentile: Top 24%
DNA and Biological Computing
0.81
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