Sex-Based Differences in Mitral Annular Disjunction Severity and Arrhythmic Risk in Mitral Valve Prolapse
In a large MVP cohort, men exhibit greater MAD length and a stronger association between iMAD length and arrhythmic events. In contrast, iMAD length in women may be less important for arrhythmic risk stratification compared to other imaging parameters such as bileaflet involvement. Further studies are needed to confirm alternative mechanisms beyond localized MAD-related myocardial traction in women with MVP.
Authors
- Lionel Tastet (ORCID: https://orcid.org/0000-0002-6374-5398)
- Dwight Bibby
- Janet J. Tang (ORCID: https://orcid.org/0000-0001-8062-2536)
- Luca Cristin (ORCID: https://orcid.org/0009-0003-2932-8659)
- Francesca N. Delling (ORCID: https://orcid.org/0000-0002-5224-4096)
- Farzin Arya
- Rohit Jhawar
- Amy H. Rich
- Qizhi Fang
Institutions
- University of California, San Francisco (US)
Publication Details
- Journal
- Journal of the American Society of Echocardiography
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1016/j.echo.2025.08.026
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39