Altered glymphatic function and cerebrovascular reactivity in white matter hyperintensities: Insights into cognitive impairment
These findings highlight the complex interplay between glymphatic dysfunction, localized CVR impairments, and cognitive decline in WMH. Preserving vascular health and optimizing glymphatic clearance may represent promising approaches for controlling WMH progression and its associated cognitive deficits.
Authors
- Xiuqin Jia
- Kai Li
- Yi Xing (ORCID: https://orcid.org/0000-0003-4931-015X)
- Yueyan Bian
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Peking University First Hospital (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111552
- Citations
- 2
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 1.82