A Case of Liver Hemorrhage Uncontrollable by Transarterial Embolization after Percutaneous Liver Biopsy in a Patient with Intravascular Large B-cell Lymphoma

Intravascular large B-cell lymphoma is a rare, aggressive lymphoma characterized by intravascular growth. The liver is a common site of involvement. Although liver biopsy provides sufficient tissue for diagnosis and treatment planning, it carries a risk of severe hemorrhage. This report describes the case of a woman in her 50s with intravascular large B-cell lymphoma who developed liver hemorrhage that was uncontrollable by transarterial embolization after undergoing ultrasound-guided percutaneous liver biopsy, necessitating laparoscopic hemostasis. Pathological findings revealed markedly dilated liver sinusoids filled with tumor cells, suggesting direct hemorrhage from these vessels. This case highlights the potential for increased hemorrhage risk in intravascular large B-cell lymphoma and underscores the necessity for careful consideration of alternative biopsy techniques, such as the transjugular approach or percutaneous biopsy with tract embolization.