High‐Calorie Diet During Pregnancy Leads to Muscular Fibrosis and Neuromuscular Damage in Offspring Mice
Maternal high-calorie diet during pregnancy induced offspring muscle atrophy and intramuscular fibrosis, especially with PolG mutation, underscoring mitochondrial dysfunction in linking maternal HFD to offspring premature aging.
Authors
- Song Ah Chae
- Jun Seok Son (ORCID: https://orcid.org/0000-0001-6807-993X)
- Yun Chun
- Min Du (ORCID: https://orcid.org/0000-0002-7232-072X)
- Hongyang Wang (ORCID: https://orcid.org/0000-0003-2858-8478)
- Zhihua Jiang
Institutions
- University of Maryland, Baltimore (US)
- Shanghai Academy of Agricultural Sciences (CN)
- Washington State University (US)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1002/jcsm.70027
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Institutes of Health