Bacterial species-structure-property relationships of polyhydroxyalkanoate biopolymers produced on simple sugars for thin film applications

This study provides a systematic comparison of PHAs from C. necator H16 and P. putida KT2440 grown on common hexoses, with full characterisation of monomer composition, molecular weight, and thermal behaviour to guide thin film bioplastic design. Blending PHB and mcl-PHA in ultrathin films revealed reduced melting points and crystallinity, likely due to reduced crystal size from film thickness constraints. This work offers a comparative reference for microbial PHA production and presents a strategy to design bioplastics with tunable properties for temperature-responsive packaging and drug delivery applications.

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Publication Details

Journal
Microbial Cell Factories
Published
2025-09-16
DOI
https://doi.org/10.1186/s12934-025-02833-7
Citations
5
Primary Topic
biodegradable polymer synthesis and properties
Type
article
Field-Weighted Citation Impact
2.99

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article

Bacterial species-structure-property relationships of polyhydroxyalkanoate biopolymers produced on simple sugars for thin film applications

Edward Attenborough, Mark M. Banaszak Holl, Farin Yazdan Parast, Leonie van ‘t Hag et al.
5 citations
Microbial Cell Factories
biodegradable polymer synthesis and properties
2.99
article

Bacterial species-structure-property relationships of polyhydroxyalkanoate biopolymers produced on simple sugars for thin film applications

Edward Attenborough, Mark M. Banaszak Holl, Farin Yazdan Parast, Leonie van ‘t Hag, Reza Nosrati
article en
5 citations

Abstract

This study provides a systematic comparison of PHAs from C. necator H16 and P. putida KT2440 grown on common hexoses, with full characterisation of monomer composition, molecular weight, and thermal behaviour to guide thin film bioplastic design. Blending PHB and mcl-PHA in ultrathin films revealed reduced melting points and crystallinity, likely due to reduced crystal size from film thickness constraints. This work offers a comparative reference for microbial PHA production and presents a strategy to design bioplastics with tunable properties for temperature-responsive packaging and drug delivery applications.

Microbial Cell FactoriesVol. 24(1)
University of Alabama at Birmingham (US), Monash University (AU)
Australian Government, Monash University, Cooperative Research Centres, Australian Government Department of Industry
Openalex Percentile: Top 9%
biodegradable polymer synthesis and properties
2.99
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Bacterial species-structure-property relationships of polyhydroxyalkanoate biopolymers produced on simple sugars for thin film applications — Edward Attenborough, Mark M. Banaszak Holl, et al. · Microbial Cell Factories (2025) | TGRS Research Map | TGRS