Defining the Rates of Cytokine Release Syndrome Associated With Talquetamab Step-up Doses
Our findings suggested that the fourth talquetamab dose could be administered in outpatient settings given its high tolerability. The reduced hospitalization period for talquetamab step-up dosing could reduce health care expenses.
Authors
- Heather Jolie Landau (ORCID: https://orcid.org/0000-0002-3152-1189)
- Kylee H. Maclachlan (ORCID: https://orcid.org/0000-0001-7873-4854)
- Hamza Hashmi (ORCID: https://orcid.org/0000-0002-4129-5867)
- Issam S. Hamadeh (ORCID: https://orcid.org/0000-0001-6628-0795)
- Saad Z. Usmani (ORCID: https://orcid.org/0000-0002-5484-8731)
- Tala Shekarkhand (ORCID: https://orcid.org/0000-0002-1404-4771)
- Malin L. Hultcrantz (ORCID: https://orcid.org/0000-0002-9045-6495)
- Aaron Philip Mitchell (ORCID: https://orcid.org/0000-0003-3639-3515)
- Gunjan L. Shah (ORCID: https://orcid.org/0000-0002-9977-0456)
- Urvi Ashok Shah (ORCID: https://orcid.org/0000-0001-8419-1091)
- Lisa Modelevsky (ORCID: https://orcid.org/0000-0002-5798-6427)
- Dhwani Patel (ORCID: https://orcid.org/0000-0003-0566-4773)
- Alexander M. Lesokhin (ORCID: https://orcid.org/0000-0001-9321-702X)
- Alice X. Wang
- Michael Scordo (ORCID: https://orcid.org/0000-0002-9484-0240)
- Hani Hassoun (ORCID: https://orcid.org/0000-0002-2036-1749)
- Sham Mailankody (ORCID: https://orcid.org/0000-0002-2815-9561)
- Neha Korde (ORCID: https://orcid.org/0000-0002-5538-4318)
- Amelia Chan (ORCID: https://orcid.org/0000-0002-0252-8883)
- Sridevi Rajeeve (ORCID: https://orcid.org/0000-0002-3458-824X)
- Sergio A. Giralt (ORCID: https://orcid.org/0000-0003-1944-5053)
- Carlyn Rose C. Tan (ORCID: https://orcid.org/0000-0001-7922-2594)
- Ross Firestone (ORCID: https://orcid.org/0000-0002-2945-9320)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1200/op-25-00224
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00